منابع مشابه
A Late Presentation of Amiodarone -Induced Hepatotoxicity
Submit Manuscript | http://medcraveonline.com oral maintenance therapy. A wide range of side effects has been reported, which tempted editors to describe the drug as Pandora’s box, Offerhaus [1]. Hepatotoxicity is a relatively uncommon side effect of amiodarone, and, although asymptomatic elevation of aminotransferases is reported in up to a fourth of all patients, symptomatic hepatic dysfuncti...
متن کاملHepatotoxicity by Acetaminophen and Amiodarone in Zebrafish Embryos
MATERIALS AND METHOD Liver is an essential organ for the detoxification of ingested chemicals and play pivotal role in various biochemical and physiological processes hence liver toxicity is one of the major causes for the withdrawal of newly discovered molecules. Peculiar characteristics viz. high fecundity rate, transparent eggs, less maintenance cost, livelihood in E3 medium without external...
متن کاملAmiodarone Hepatotoxicity with Absent Phospholipidosis and Steatosis: A Case Report and Review of Amiodarone Toxicity in Various Organs
We present the first description of amiodarone toxicity in the liver without phospholipidosis or steatosis. In doing so, we will review the various effects of amiodarone toxicity in various organs. The patient is a young adult who had cardiac reconstruction as a child for transposition of the great vessels. A needle biopsy was taken due to elevated liver enzymes. Her ALT was 188 U/L (5-50) and ...
متن کاملGranular cells as a marker of early amiodarone hepatotoxicity: a pathological and analytical study.
Two contrasting cases of amiodarone hepatotoxicity are described. In one, perivenular collections of swollen cells, probably macrophages, with granular cytoplasm in an otherwise nearly normal liver were observed. Transmission electron microscopy showed that the cytoplasmic granularity was due to lysosomal bodies of various sizes. X-ray energy and wavelength spectroscopic analysis showed a high ...
متن کاملAmiodarone pneumonitis.
Amiodarone is an iodinated benzofuran derivative that is widely used for the treatment of cardiac arrhythmia. The drug has an extensive adverse effect profile that involves the liver, thyroid, cornea, skin, lung, bone marrow, and neuromuscular system. Pulmonary toxicity is the most serious adverse reaction, and it often limits the drug’s clinical use.1,2 We encountered a patient with suspected ...
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ژورنال
عنوان ژورنال: Digestive Diseases
سال: 1997
ISSN: 1421-9875,0257-2753
DOI: 10.1159/000171606